Hypergravity Suppresses Bone Resorption in Ovariectomized Rats
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چکیده
INTRODUCTION: The effects of gravity on bone metabolism are unclear. Most studies in humans and laboratory animal models have revealed that exposure to microgravity during spaceflight leads to bone loss, but the details of its mechanism are still unclear. On the other hand, some studies have reported the effects of hypergravity on mature skeleton, but the details of the effect of hypergravity on bone metabolism have not been well documented. The present study was undertaken to delineate the influence of hypergravity on the mature skeleton in vivo and to assess the effect of hypergravity on osteoclasts and osteoblasts in vitro.
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تاریخ انتشار 2010